Multimodal Brain Pathology Detection

Plasma-CycleGAN: Plasma Biomarker-Guided MRI to PET Cross-Modality Translation Using Conditional CycleGAN

Yanxi Chen, Yi Su, Celine Dumitrascu, Kewei Chen, David Weidman, Richard J Caselli, Nicholas Ashton, Eric M Reiman, Yalin Wang

 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), Apr. 2025 [oral]


Enhancing Alzheimer’s Diagnosis: Leveraging Anatomical Landmarks in Graph Convolutional Neural Networks on Tetrahedral Meshes

Yanxi Chen, Mohammad Farazi, Zhangsihao Yang, Yonghui Fan, Nicholas Ashton, Eric M Reiman, Yi Su, Yalin Wang

Information Processing In Medical Imaging (IPMI), Jun. 2025


Combining Blood-Based Biomarkers and Structural MRI Measurements to Distinguish Persons With and Without Significant Amyloid Plaques

Yanxi Chen, Yi Su, Jianfeng Wu, Kewei Chen, Alireza Atri, Richard J Caselli, Eric M. Reiman, Yalin Wang, for the Alzheimer’s Disease Neuroimaging Initiative

Journal of Alzheimer’s Disease, 2024


A Surface-Based Federated Chow Test Model for Integrating APOE Status, Tau Deposition Measure, and Hippocampal Surface Morphometry

Wu J, Su Y, Chen Y, Zhu W, Reiman EM, Caselli RJ, Chen K, Thompson PM, Wang J, Wang Y

Journal of Alzheimer’s Disease, 2023


Improved Prediction of Beta-Amyloid and Tau Burden Using Hippocampal Surface Multivariate Morphometry Statistics and Sparse Coding

Wu J, Su Y, Zhu W, Jalili Mallak N, Lepore N, Reiman EM, Caselli RJ, Thompson PM, Chen K, Wang Y, ADNI Group

Journal of Alzheimer’s Disease, 2022


Predicting Brain Amyloidosis with Plasma B-Amyloid42/40 and MRI-Based Morphometry Features

Wu J, Su Y, Thompson PM, Reiman EM, Caselli RJ, Chen K, Wang Y

IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), Mar. 2022


Investigating the Effect of Tau Deposition and Apoe on Hippocampal Morphometry in Alzheimer’s Disease: A Federated Chow Test Model

Wu J, Su Y, Reiman EM, Caselli RJ, Chen K, Thompson PM, Wang J*, Wang Y*

 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), Mar. 2022


Federated Morphometry Feature Selection for Hippocampal Morphometry Associated Beta-Amyloid and Tau Pathology

Wu J, Dong Q, Zhang J, Su Y, Wu T, Caselli RJ, Reiman EM, Ye J, Lepore N, Chen K, Thompson PM, Wang, Y, ADNI Group,

Frontiers in Neuroscience, section Brain Imaging Methods, 2021


Predicting Brain Amyloid Using Multivariate Morphometry Statistics, Sparse Coding, and Correntropy: Validation in 1,101 Individuals From the ADNI and OASIS Databases

Wu J, Dong Q, Gui J, Zhang J, Su Y, Chen K, Thompson PM, Caselli RJ, Reiman EM, Ye J, Wang Y, ADNI Group

Frontiers in Neuroscience, section Brain Imaging Methods, 2021, In Press.